Bacillus velezensis A2 fermentation exerts a protective effect on renal injury induced by Zearalenone in mice.
MouseChemical/toxinKunmingFemalen = Four groups of 10 mice per group (40 total)Oral gavage, without anaesthesia0.2 mL of A2 LB fermentation broth per animal per day, co-a…Co-administered with zearalenone in the same daily gavage
Model: Zearalenone-induced renal injury by daily oral gavage of 40 mg/kg zearalenone for 28 days
Co-administration of A2 fermentation broth reduced zearalenone-induced glomerular lobulation and atrophy, restored kidney index, lowered serum blood urea nitrogen, uric acid and creatinine (P < 0.01), inhibited the rise in malondialdehyde, restored total superoxide dismutase and glutathione peroxid…
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