PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2018

Salicornia ramosissima J. Woods seeds affected the normal regenerative function on carbon tetrachloride-induced liver and kidney injury.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 30098546 ↗2018Reported harm

Salicornia ramosissima J. Woods seeds affected the normal regenerative function on carbon tetrachloride-induced liver and kidney injury.

MouseChemical/toxinMaleOral2000 mg/kg/dayAdministered before carbon tetrachloride in the protection setting and after ca…

Model: Carbon tetrachloride-induced acute liver and kidney injury (0.2 mL/kg), studied as seed effects alone, protection against acute carbon tetrachloride toxicity, and regeneration after acute carbon tetrachloride exposure

Seed powder alone produced slightly enlarged hepatic sinusoids and noticeable renal inflammation, gave no protection against carbon tetrachloride toxicity and did not aid hepatic or renal recovery, with the authors reporting apparent synergism between the seeds and carbon tetrachloride under these…

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.