Transcriptomic analysis of lung tissues after hUC-MSCs and FTY720 treatment of lipopolysaccharide-induced acute lung injury in mouse models.
MouseEndotoxin/LPSC57BL/6Female
Model: Lipopolysaccharide-induced acute lung injury and acute respiratory distress syndrome
Mesenchymal stem cells and FTY720 each alleviated lipopolysaccharide-induced lung injury, and the combination was more effective than either alone. Transcriptomic analysis identified Gene Ontology and pathway terms and candidate target genes associated with treatment.
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