Ameliorating role of methanolic leaves extract of Fraxinus xanthoxyloides against CCl4-challanged nephrotoxicity in rats.
RatChemical/toxinSprague-DawleyMale
Model: Carbon tetrachloride-induced nephrotoxicity
Carbon tetrachloride impaired renal function, depleted antioxidant enzymes and increased lipid peroxidation and DNA damage. Co-treatment with the leaf extract, like silymarin, restored the measured parameters towards control values.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.