The anti-inflammatory and anti-oxidative actions of eugenol improve lipopolysaccharide-induced lung injury.
MouseEndotoxin/LPSBALB/cMaleSeveral doses tested with a dose-dependent effect; mechanis…
Model: Lipopolysaccharide-induced acute lung injury, with lung mechanics and histology analysed 24 h after exposure
Eugenol improved lipopolysaccharide-induced lung functional and histological changes in a dose-dependent way, and at 150 mg/kg inhibited release of inflammatory cytokines, NADPH oxidase activity and protein oxidation.
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