Novel Lipid Signaling Mediators for Mesenchymal Stem Cell Mobilization during Bone Repair.
MixedFractureCalvarial/defectAcute mobilisation of mesenchymal stem cells detected as early as 1.5 h after t…
Model: Critically sized rat cranial (calvarial) defect and bone morphogenetic protein-2 induced ectopic bone formation
VPC01091 mobilised mesenchymal stem cells into blood within 1.5 h, increased bone morphogenetic protein-2 induced ectopic bone and significantly increased new bone formation in critically sized rat cranial defects without impeding engraftment of transplanted mesenchymal stem cells.
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