PRECLINICAL PUBLICATION · 2018

Protective effect of polysaccharide from Agaricus bisporus in Tibet area of China against tetrachloride-induced acute liver injury in mice.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Agaricus bisporus polysaccharide (FPS)

PMID 29969638 ↗2018Reported benefit

Protective effect of polysaccharide from Agaricus bisporus in Tibet area of China against tetrachloride-induced acute liver injury in mice.

MouseChemical/toxinICR

Model: Carbon tetrachloride-induced acute liver injury

FPS significantly lowered liver index, serum GGT, ALT, ALP and AST and hepatic malondialdehyde, raised hepatic glutathione and superoxide dismutase, alleviated histological liver damage and reduced TGF-beta1 and Smad3 expression.

Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.