In vivo wound-healing activity of Euphorbia characias subsp. wulfenii: Isolation and quantification of quercetin glycosides as bioactive compounds.
MixedWoundSprague-Dawley rats (mouse strain not stated)MaleTopical application to wounds (ointment); systemic route for anti-inflammatory assay not specified
Model: Linear incision and circular excision skin wound models, with acetic acid-induced increase in capillary permeability as an acute inflammation model
The methanol extract of the aerial parts showed significant wound healing activity (43.04% in the linear incision model, 65.24% in the circular excision model) and 34.74% anti-inflammatory activity. Bioassay-guided fractionation identified quercitrin, hyperoside and guaijaverin as the active consti…
Extraction: extract · Supplied extraction confidence: 0.66. Machine-extracted fields require source verification.