PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2018

Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29902864 ↗2018Reported benefit

Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress.

MouseChemical/toxinICRMale

Model: Acute ethanol-induced liver injury

SCAP reduced serum and supernatant alanine and aspartate aminotransferase, lowered hepatic triglyceride and malondialdehyde, increased superoxide dismutase activity, improved liver histopathology and inhibited ethanol-induced upregulation of CYP2E1.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.