Protective role of beta-carotene against oxidative stress and neuroinflammation in a rat model of spinal cord injury.
RatSpinal cord injuryUnspecifiedSprague-DawleyMale
Model: Acute spinal cord injury
beta-Carotene substantially improved locomotor function reduced by spinal cord injury, lowered oxidative stress markers, restored Nrf2 and HO-1 expression, reduced pro-inflammatory cytokines and COX-2, inhibited astrocyte activation and blocked NF-kappaB pathway activation.
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.