Comparison of cAMP with other radioprotectors against chronic damage to the rat parotid gland.
RatRadiationFemale
Model: Radiation injury of the parotid gland, assessed in acute (first week) and chronic (60 to 90 day) phases
Cyclic AMP protected the parotid gland during the acute phase and remained protective against chronic damage, with a dose modification factor of 1.86 for gland weight. Chronic damage was about 1.5 times as great as acute damage, and protection against acute and chronic damage was approximately equa…
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