Tissue-engineered biological dressing accelerates skin wound healing in mice via formation of provisional connective tissue.
MouseWoundTopical application to the wound bed
Model: Full-thickness excisional splinted skin wound
The cell-based skin equivalent filled the wound bed immediately and produced simultaneous reorganisation of the dermal component into highly vascularised granulation-like tissue with rapid epithelialisation, improving healing quality. Inflammation was delayed and less pronounced. Acellular collagen…
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