Cetuximab and Taxol co-modified collagen scaffolds show combination effects for the repair of acute spinal cord injury.
RatSpinal cord injuryComplete transectionSprague-DawleyFemaleImplantation into the spinal cord lesion siteImmediately after injury (acute)
Model: Complete spinal cord transection with removal of 4 mm of spinal tissue
Implantation of the cetuximab and Taxol co-modified collagen scaffold increased neural regeneration and reconnection of the neural network, decreased deposition of scar-related inhibitors within the lesion centre and improved motor function relative to controls, indicating a combination effect of t…
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