Topical Lyophilized Targeted Lipid Nanoparticles in the Restoration of Skin Barrier Function following Burn Wound.
MouseBurnUnspecifiedmaleTopical, dispersed in hydrogel
Model: Full-thickness burn wound
Topical application of hydrogel-dispersed lyophilised TLN carrying LNA anti-miR-107 twice a week significantly accelerated wound closure and restoration of skin barrier function, depleted miR-107, upregulated dicer and significantly increased junctional protein expression.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.