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PRECLINICAL PUBLICATION · 2018

Stem Cells from Human Exfoliated Deciduous Teeth Modulate Early Astrocyte Response after Spinal Cord Contusion.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29796991 ↗2018Reported benefit

Stem Cells from Human Exfoliated Deciduous Teeth Modulate Early Astrocyte Response after Spinal Cord Contusion.

RatSpinal cord injuryContusionWistarmaleIntraspinal transplantation1 h after injury

Model: Spinal cord contusion produced with the NYU Impactor following laminectomy

Acute SHED transplantation promoted functional recovery from the first week after contusion, increased spinal vimentin-positive cells at 24 and 48 h, increased S100B and Kir4.1 bioavailability and reduced glial scar formation, consistent with a paracrine neuroprotective action.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.