PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2018

OA-GL21, a novel bioactive peptide from, accelerated the healing of skin wounds.

Mouse / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29752337 ↗2018Reported benefit

OA-GL21, a novel bioactive peptide from, accelerated the healing of skin wounds.

MouseWoundMalen = 20 mice total across 4 groups; n = 5 wounds per group for a…Topical to wound20 uL of 1, 10 or 100 ug/mL applied topically per woundStarted on the day of wounding

Model: Two 8 x 8 mm full-thickness excisional skin wounds created on the shaved back under 1% pentobarbital sodium anaesthesia (0.1 mL/20 g intraperitoneally)

OA-GL21 at 100 ug/mL accelerated closure with thinner neoepidermis and better granulation than saline and Kangfuxin; 10 ug/mL matched Kangfuxin 10 mg/mL; 1 ug/mL was ineffective.

Extraction: extract · Supplied extraction confidence: 0.88. Machine-extracted fields require source verification.