Topical oral wound healing potential of anthocyanin complex: animal and clinical studies.
RatWoundWistarn = 68 volunteers in the randomised double-blind clinical trial…Topical application to the oral mucosa10% w/w anthocyanin complex in a mucoadhesive gelAfter wounding
Model: Topical acute oral mucosal wounds in rats and acute orthodontic oral wounds in volunteers
The 10% w/w anthocyanin gel reduced erythema and oral wound size in rats more than placebo gel, and in 68 orthodontic volunteers produced significant wound size reduction and enhanced wound closure by day 3 compared with placebo.
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