Maslinic acid protects against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
MouseEndotoxin/LPSBALB/cIntraperitoneal1 h before lipopolysaccharide and d-galactosamine challenge
Model: Acute liver injury induced by lipopolysaccharide plus d-galactosamine
Maslinic acid reduced histopathological liver damage, serum AST and ALT, inflammatory cytokines, MDA and myeloperoxidase in a dose-dependent manner, lowered hepatic NF-kappaB and raised Nrf2 and HO-1 expression.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.