Motor Cortex Stimulation Regenerative Effects in Peripheral Nerve Injury: An Experimental Rat Model.
RatOtherSprague-DawleyMalen = 80 rats, 20 per group across 4 groupsAcute arm stimulated for 15 minutes immediately after nerve section and suture;…
Model: Right sciatic nerve section followed by immediate microsurgical epineural suture
Motor cortex stimulation improved functional recovery, nerve regeneration and muscle reinnervation from week 4 onwards compared with unstimulated controls (P<0.05), and produced higher reinnervation rates than peripheral nerve stimulation, with the best results in the acute stimulation group.
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