PRECLINICAL PUBLICATION · 2018

Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogels promote complete skin regeneration.

Mouse / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogel, and poly(sulfobetaine methacrylate) incorporated into poly(ethylene glycol) hydrogels

PMID 29535009 ↗2018Reported benefit

Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogels promote complete skin regeneration.

MouseWoundMaleTopical application to the wound as a dressing

Model: Full-thickness excisional cutaneous wounds in mice

Poly(sulfobetaine methacrylate) hydrogels improved full-thickness wound regeneration relative to poly(ethylene glycol) hydrogels by enhancing angiogenesis, reducing inflammation and modulating macrophage polarisation.

Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.