Lafoensia pacari A. St.-Hil.: Wound healing activity and mechanism of action of standardized hydroethanolic leaves extract.
RatWoundWistar for the rat wound models; mice used for acute toxicity and lipopolysaccharide-induced peritonitisTopical for the wound models and oral for the peritonitis modelTopical 10 and 30 mg/g of gel in the excision model and 10,…
Model: Excision and incision skin wound models in rats, with lipopolysaccharide-induced peritonitis in mice as a separate anti-inflammatory model
Topical extract increased wound contraction with complete re-epithelialisation at 22.0 plus or minus 1.5 days for 10 mg/g (p less than 0.05) and 21.7 plus or minus 1.6 days for 30 mg/g (p less than 0.01), increased tensile break strength in incised wounds and reduced leukocyte migration in peritoni…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.