PRECLINICAL PUBLICATION · 2018

Protective Effects of Cornel Iridoid Glycoside in Rats After Traumatic Brain Injury.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Cornel iridoid glycoside, the active fraction of Cornus officinalis

PMID 29492766 ↗2018Reported benefit

Protective Effects of Cornel Iridoid Glycoside in Rats After Traumatic Brain Injury.

RatTBIUnspecifiedSprague-DawleyMaleIntragastric

Model: Traumatic brain injury induced in the right cerebral cortex of adult male rats

Treatment improved neurological and cognitive scores, reduced neuronal loss and S100beta, raised the Bcl-2 to Bax ratio and lowered caspase-3 acutely, and increased neurotrophic and synaptic proteins after 30 days.

Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.