Effects of gangliosides on expressions of caspase-3 and NGF in rats with acute spinal cord injury.
RatSpinal cord injuryUnspecifiedSprague-DawleyMaleAfter injury
Model: Acute spinal cord injury
Spinal cord injury lowered locomotor scores, raised malondialdehyde and caspase-3 and lowered superoxide dismutase and NGF. GM1 treatment reduced malondialdehyde, increased superoxide dismutase activity, downregulated caspase-3 mRNA and protein and upregulated NGF mRNA and protein, with significant…
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