Radioprotective and radiomitigative effects of BP-C2, a novel lignin-derived polyphenolic composition with ammonium molybdate, in two mouse strains exposed to total body irradiation.

Radioprotective and radiomitigative effects of BP-C2, a novel lignin-derived polyphenolic composition with ammonium molybdate, in two mouse strains exposed to total body irradiation.

Model: Total body irradiation, 4.0 to 8.0 Gy

BP-C2 improved 30-day survival (dose reduction factor 1.1) and increased endogenous spleen colony-forming units. After 5.0 Gy, colony-forming units were 6.7 +/- 5.1 with BP-C2 versus 2.3 +/- 2.3 with placebo (p = 0.0245) and surviving intestinal crypts were 133.7 +/- 13.9 versus 124.2 +/- 10.5 (p <…

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.