Protective effect of baicalin against severe burn-induced remote acute lung injury in rats.
RatBurnUnspecifiedFemale
Model: Severe burn with remote acute lung injury
Baicalin lowered the lung wet-to-dry weight ratio, improved pulmonary histology and reduced HMGB1, TNF-alpha, IL-8, IL-1beta and IL-18, myeloperoxidase activity and malondialdehyde while raising superoxide dismutase. NLRP3, caspase-1, NF-kappaB and MMP-9 protein expression were suppressed.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.