Impacts of Bone Marrow Stem Cells on Caspase-3 Levels after Spinal Cord Injury in Mice.
MouseSpinal cord injuryCompressionBALB/cMalen = 42 mice total: control n=12, sham n=18, experimental n=12,…Intravenous2 x 10 to an exponent not rendered in the retrieved full te…1 day after injury
Model: Spinal cord injury at T10 by bilateral compression for 2 min after exposure of the vertebral column between T7 and T11 and drilling to expose intact dura
Intravenous bone marrow mesenchymal stem cells significantly lowered caspase-3 compared with untreated injured mice at 21 days (0.4 plus or minus 0.095 versus 0.793 plus or minus 0.076) and 35 days (0.223 plus or minus 0.027 versus 0.643 plus or minus 0.058), both p less than 0.001
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.