Preparation, characterization, and evaluation of 3,6-O-N-acetylethylenediamine modified chitosan as potential antimicrobial wound dressing material.
MixedWound
Model: Full-thickness skin wound model used for preliminary evaluation of wound healing rate, alongside haemolysis, cytotoxicity, bovine serum albumin adsorption and acute toxicity testing
AEDMCS with 90.3% deacetylation and a degree of substitution of 0.72 showed reduced thermostability and crystallinity but greatly improved solubility relative to chitosan, and higher antibacterial activity against six bacteria that commonly cause wound infection. It had acceptable haemolysis and cy…
Extraction: extract · Supplied extraction confidence: 0.45. Machine-extracted fields require source verification.