PebbleAtlas
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PRECLINICAL PUBLICATION · 2017

Protective roles and mechanisms of Dendrobium officinal polysaccharides on secondary liver injury in acute colitis.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29074081 ↗2017Reported benefit

Protective roles and mechanisms of Dendrobium officinal polysaccharides on secondary liver injury in acute colitis.

MouseChemical/toxinBALB/cMale

Model: Secondary liver injury in acute colitis induced by 4% dextran sodium sulfate (DSS); LPS-stimulated RAW264.7 cells in vitro

DOPS attenuated DSS-induced hepatic damage, inflammation and oxidative stress in vivo and in vitro through TNF-alpha suppression and Nrf2 activation

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.