Isoflavonoids as wound healing agents from Ononidis Radix.
MixedWoundSprague-Dawley rats (MeSH indexed); mouse strain not statedMaleIn vivo dose not stated; isolated compounds tested at 100 m…
Model: Linear incision and circular excision cutaneous wound models; carrageenan-induced hind paw oedema, TPA-induced ear oedema, acetic acid-induced capillary permeability and Freund complete adjuvant-induced arthritis as inflammation models
Fraction Fr-E5 increased incision wound tensile strength by 33.4%, reduced excision wound area by 51.4% at day 12 and gave tissue hydroxyproline of 30.9 plus or minus 0.72 micrograms/mg, with 40.3% inhibition of capillary permeability and 28.1 to 32.2% inhibition of carrageenan paw oedema, but no a…
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.