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PRECLINICAL PUBLICATION · 2017

Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair.

Mouse / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28978794 ↗2017Reported benefit

Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair.

MouseWoundTopical scaffold transplantation onto the wound

Model: Cutaneous wound model in wild-type and diabetic mice; wound geometry and creation method not stated in the available text

Delivering supra-physiologic numbers of monocytes or macrophages on a pullulan-collagen composite hydrogel scaffold significantly accelerated wound healing in both wild-type and diabetic mice with no adverse effect on repair quality, with transplanted cells adopting shifting M1 and M2 proportions a…

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