Effects of different suture materials on tissue healing.
RatWoundSprague-Dawleymalen = 20 male rats, 10 per sacrifice time point, each providing f…surgical placement as skin suturessize 3-0 sutureat the time of wounding
Model: Four 1 cm longitudinal dorsal skin incision wounds per animal under ketamine anaesthesia, closed primarily with a standard two clockwise and one anticlockwise knot technique
No statistically significant differences were found between the four materials for cell density, necrosis, fibrosis, foreign body reaction or acute and chronic inflammatory cells at either time point. Fibrosis, acute inflammatory cells and foreign body reaction all increased significantly from day…
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