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PRECLINICAL PUBLICATION · 2017

Early Transient Mild Hypothermia Attenuates Neurologic Deficits and Brain Damage After Experimental Subarachnoid Hemorrhage in Rats.

Rat / Haemorrhage/shock

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28951276 ↗2017Reported benefit

Early Transient Mild Hypothermia Attenuates Neurologic Deficits and Brain Damage After Experimental Subarachnoid Hemorrhage in Rats.

RatHaemorrhage/shockUnspecifiedSprague-DawleyMalen = 20 male Sprague-Dawley ratsActive surface coolingTarget temperature 34 degrees C (controls maintained at 37.…Early, in the acute phase after subarachnoid haemorrhage; effects on cerebral p…

Model: Experimental subarachnoid haemorrhage

Hypothermia improved cerebral perfusion pressure in the first 60 minutes after subarachnoid haemorrhage through a slight increase in mean arterial blood pressure and a significant reduction in intracranial pressure, with a trend to increased cerebral blood flow. The rate of injured hippocampal neur…

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.