The identification of functional proteins from amputated lumbricus Eisenia fetida on the wound healing process.
MouseWoundICR
Model: Acute cutaneous wound (in vivo), with parallel in vitro work in NIH 3T3 fibroblasts and HaCaT keratinocytes
Among three salted-out fractions of G-90', ES2 showed significant wound healing activity by promoting fibroblast and keratinocyte proliferation and stimulating fibroblast growth factor and vascular endothelial growth factor expression in the wound area. Two proteins in ES2 were identified by bottom…
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