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PRECLINICAL PUBLICATION · 2017

Phytochemical characterization and bioactivity of Lycium europaeum: A focus on antioxidant, antinociceptive, hepatoprotective and nephroprotective effects.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28946192 ↗2017Reported benefit

Phytochemical characterization and bioactivity of Lycium europaeum: A focus on antioxidant, antinociceptive, hepatoprotective and nephroprotective effects.

MouseChemical/toxinMalePretreatment, before carbon tetrachloride administration

Model: Carbon tetrachloride-induced hepatic and renal injury in mice; analgesia assessed by hot-plate and acetic acid writhing tests

Carbon tetrachloride raised serum liver and renal biomarkers and tissue malondialdehyde, and pretreatment with the Lycium europaeum methanol fraction or quercetin significantly restored most of these parameters towards normal with improvement in histopathology. The methanol fraction also reduced ac…

Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.