Pro-Regenerative Hydrogel Restores Scarless Skin during Cutaneous Wound Healing.
MouseWoundTopical application to the wound
Model: Acute deep dermal cutaneous wound in murine and porcine models
DexIEME hydrogel showed superior biocompatibility with low proinflammatory response, promoted M2 macrophage phenotype, and produced complete skin regeneration with hair regrowth on pre-existing scars in mice and regenerated skin in deep porcine wounds, while untreated scars remained intact.
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