Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats.
RatTBIUnspecifiedWistarMaleIntravenous, lateral tail vein injectionImmediately after fimbria-fornix transection or sham surgery
Model: Fimbria-fornix transection, an experimental traumatic brain injury model
Task acquisition was significantly impaired in fimbria-fornix transected animals, but UCCB01-144 had no significant effect on spatial delayed alternation after transection or sham surgery, although decelerated learning curves were seen after treatment in transected animals.
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.