Novel transparent collagen film patch derived from duck's feet for tympanic membrane perforation.
RatWoundSprague-Dawleyn = 48 tympanic membranes from 24 rats, 16 membranes per groupTopical patch applied over the perforation
Model: Acute traumatic tympanic membrane perforation created surgically in both ears
All three groups healed within 14 days, but healing was faster with the duck's feet collagen film patch than with paper patch or spontaneous healing; the patch showed no cytotoxicity, supported greater early cell proliferation, and was transparent and biodegradable so did not require removal.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.