Rescue effects of ginger extract on dose dependent radiation-induced histological and biochemical changes in the kidneys of male Wistar rats.
RatRadiationWistarMalePretreatment for 10 days before irradiation
Model: Whole body gamma irradiation at 2, 4 or 8 Gy causing kidney injury
Ten days after whole body gamma irradiation, glomerular and tubular cell proliferation and glomerular and peritubular fibrosis were seen, with significant rises in 8-OHdG, C-reactive protein, cystatin C (at 8 Gy), plasma urea and creatinine, and a significant fall in total antioxidant capacity rela…
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