Reduction in Temporary and Permanent Audiological Injury Through Internal Jugular Vein Compression in a Rodent Blast Injury Model.
RatOtherSprague-DawleyMalen = 20 rats, 10 with collar application and 10 withoutExternal application to the neckNot applicable; one collar per animalCollar in place at the time of blast injury
Model: Right-sided blast shock wave exposure at 16.8 plus or minus 0.3 PSI (195.3 dB SPL)
Internal jugular vein compression at the time of blast significantly reduced tympanic membrane rupture and the initial temporary threshold shift on otoacoustic emissions in both ears. At 28 days, collared animals returned to baseline otoacoustic emission values whereas non-collared animals had a pe…
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