Laminin mimetic peptide nanofibers regenerate acute muscle defect.
RatOtherSprague-DawleyMaleLocal injection into the injured tibialis anterior muscleAdministered at the time of acute muscle injury
Model: Acute skeletal muscle defect created in the tibialis anterior muscle
Laminin-mimetic peptide nanofibres significantly promoted satellite cell activation and accelerated myofibrillar regeneration after acute muscle injury in rats. Treatment reduced the time required for structural and functional repair of the skeletal muscle without additional cell or growth factor t…
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