Impact of Acute Intestinal Ischemia and Reperfusion Injury on Hemodynamics and Remote Organs in a Rat Model.
RatIschaemia-reperfusionIntestinal / mesentericWistarMalen = n = 6 per group across four groupsIntravenous infusionTitrated according to cardiac output; absolute volumes not…Administered during the reperfusion phase
Model: Acute mesenteric ischaemia and reperfusion produced by superior mesenteric artery occlusion for 90 minutes followed by 120 minutes of reperfusion, with ventilation and haemodynamic monitoring
Colloid resuscitation with Geloplasma required significantly less volume than Ringer's solution and was associated with less metabolic acidosis, although cardiac output still declined in the late phase.
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