Salidroside Attenuates LPS-Induced Acute Lung Injury in Rats.
RatEndotoxin/LPSSprague-Dawley20 mg/kg and 40 mg/kg
Model: Endotoxaemic acute lung injury induced by lipopolysaccharide 15 mg/kg
Salidroside attenuated lung oedema, histological injury, neutrophil infiltration and inflammatory cytokines while restoring antioxidant activity, apparently through inhibition of caveolin-1 and TLR/NF-kappaB signalling.
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