The Effect of Pycnogenol on Wound Healing in Diabetic Rats.
RatWoundSprague-DawleyMalen = 48 adult male rats, 24 of them diabetic, with 6 animals fro…Topical30 mg of powder per woundFrom wounding onwards
Model: Three full-thickness excisional skin wounds of 1.3 cm by 1.3 cm by 2 mm per animal, in healthy rats and in rats made diabetic with a single dose of alloxan
Pycnogenol-treated wounds showed greater average size reduction at 58.03 per cent than untreated wounds at 45.73 per cent or cleanser and silver sulfadiazine treated wounds at 48.73 per cent, with higher collagen deposition and neovascularisation scores in diabetic rats.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.