Temporary skin grafts based on hybrid graphene oxide-natural biopolymer nanofibers as effective wound healing substitutes: pre-clinical and pathological studies in animal models.
RatWoundSprague-DawleyMaleTopical application as a temporary skin graft1.5 wt% graphene oxide nanosheets in the nanofibre membrane
Model: Large open full-thickness excisional skin wound, 1.5 x 1.5 cm
Large open wounds were fully regenerated 14 days after operation with the graft, and over 99% wound healing occurred by 21 days with the 1.5 wt% graphene oxide graft, whereas the gauze control required considerably longer. Pathology showed thick dermis formation and complete epithelialisation in th…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.