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PRECLINICAL PUBLICATION · 2017

Bone-Marrow-Derived Endothelial Progenitor Cell Treatment in a Model of Lateral Fluid Percussion Injury in Rats: Evaluation of Acute and Subacute Outcome Measures.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28335684 ↗2017Mixed findings

Bone-Marrow-Derived Endothelial Progenitor Cell Treatment in a Model of Lateral Fluid Percussion Injury in Rats: Evaluation of Acute and Subacute Outcome Measures.

RatTBIFluid percussionSprague-DawleyMale

Model: Lateral fluid percussion injury

EPC treatment reduced activated caspase-3 and PARP cleavage at 72 h post-injury and significantly improved rotarod locomotor performance, but had non-significant effects on microvascular outcome, hippocampal neuronal density and spatial memory at 30 days.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.