PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2017

Wound Healing Effect ofgel on Excisional Wounds in Rats.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28217647 ↗2017Reported benefit

Wound Healing Effect ofgel on Excisional Wounds in Rats.

RatWoundn = 36 rats divided into three groupsTopical10% extract concentration in gelStarted on the day the wounds were created

Model: Standard 1 cm circular full-thickness excisional wound on the posterior back created with a surgical knife under general anaesthesia with xylazine 10 mg/kg intraperitoneally and ketamine 5 mg/kg

Mean wound closure rate was 15.52 mm/day with the extract gel versus 8.51 mm/day for vehicle gel and 5.01 mm/day for saline. Fibroblast production was about 61% higher than saline control (p < 0.05) and collagen bundle density about 41% higher than saline and about 34% higher than vehicle (p = 0.03…

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.