PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2017

Lycopene in the Prevention of Radiation-Induced Esophagitis.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28094572 ↗2017Reported benefit

Lycopene in the Prevention of Radiation-Induced Esophagitis.

RatRadiationWistar albinon = 60 rats in 5 groups6 mg/kg body weight per day7 days before radiotherapy in the lycopene plus radiotherapy group, and 7 days…

Model: Radiation-induced acute oesophagitis after 35 Gy thoracic radiotherapy

Both lycopene schedules gave better histopathological results than radiotherapy alone. Grade 2 to 3 degenerative changes with necrosis and vacuole formation were significantly less frequent in both lycopene groups, with a trend to less subepithelial bulla formation and inflammation. Regeneration an…

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.