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PRECLINICAL PUBLICATION · 2016

TGF-beta1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.

Mouse / Haemorrhage/shock

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 27893460 ↗2016Reported benefit

TGF-beta1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.

MouseHaemorrhage/shockUnspecifiedAdministered following intracerebral haemorrhage; exact interval not stated in…

Model: Murine intracerebral haemorrhage; model details not specified in the available text

TGF-beta1 treatment after intracerebral haemorrhage reduced microglial Il6 expression and improved functional outcomes in mice. Patients with early increases in plasma TGF-beta1 had better outcomes at 90 days.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.