Protective effect of Silybum marianum and Taraxacum officinale extracts against oxidative kidney injuries induced by carbon tetrachloride in rats.
RatChemical/toxinWistar albinoFemalen = 66 female rats in total across six groups, n per group not…Oral gavage100 mg/kg/day of each extractPretreatment, extracts started 10 days before CCl4 administration
Model: Carbon tetrachloride induced oxidative kidney injury, CCl4 in olive oil 1:1 at 1.5 mL/kg intraperitoneally
Both extracts reduced CCl4-induced rises in serum ALP, GGT and renal MDA and restored GSH and glutathione-dependent enzyme activities with improved histopathology, with Silybum marianum the more effective of the two.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.