Antibodies raised against divalent type b flagellin and pilin provide effective immunotherapy against Pseudomonas aeruginosa infection of mice with burn wounds.
MouseBurnUnspecifiedBALB/cmaleProphylactic administration, therapeutic administration, and a combined prophyl…
Model: Burn wound with Pseudomonas aeruginosa infection
Antibodies against flagellin b plus PilA showed synergistic improvement of opsonophagocytosis and reduction of cell invasion compared with monovalent antibodies. Prophylactic and combined prophylactic plus therapeutic regimens improved survival of mice infected with disparate Pseudomonas aeruginosa…
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